Margaret Takako Hicken
Broadly speaking, I examine the ways in which social forces link racial group membership to the risk of poor health, particularly those conditions related to cardiovascular and renal diseases. In the US, despite tremendous resources devoted to the elimination of health inequalities, evidence suggests that they are growing. I would argue that our inability to eliminate (or even reduce) these inequalities is due to a lack of truly interdisciplinary approaches. Throughout my research program, I ground my approach to the study of race in the social sciences while integrating the biological sciences to ensure that the mechanisms I examine are both socially- and biologically-plausible. Under this broad umbrella of social determinants of health inequalities, I maintain two distinct research themes.
Research Theme 1: Vigilance. Within the first research theme, I draw from traditions in sociology, cultural anthropology, and psychology to study the notion of “racism-related vigilance” or “vigilant coping style” and its relation to the health of Black Americans. Many hypothesize that stress plays an important role in health inequalities. However, the empirical literature is remarkably small with mixed results. I would argue that this is because we have not adequately conceptualized the types of social stress that are salient to Black Americans. Ethnographers and qualitative sociologists have long-documented thoughts and behaviors of their Black study participants in which they mentally prepare to negotiate social spaces in American society. Psychologists argue that this type of anticipatory and ruminative stress – or vigilance – is particularly toxic for health.
Research Theme 2: Social & Physical Environment. In my second research program, I examine the social and physical environment as drivers of racial health inequalities. My earlier work focused on the intersection of social adversity and environmental toxicants, supporting the notion that social adversity increases vulnerability to the health effects of environmental hazards. Over the past two years, I have begun to focus more on residential neighborhoods, particularly on racial segregation, as drivers of the racial health inequalities. Furthermore, I integrate social science information on segregation and neighborhood characteristics with biomedical information on genetics and molecular pathways that may link the social exposures to disease risk. Specifically, I examine gene-environment interactions that may drive racial inequalities in kidney disease, through the differences in gene expression of inflammation pathways, hypothesizing that inequities in neighborhood characteristics enhance genetic risk to result in disease inequalities.
- Margaret Takako Hicken, Payne-Sturges, Devon, Ember McCoy. 2023. Evaluating Race in Air Pollution and Health Research: Race, PM2.5 Air Pollution Exposure, and Mortality as a Case Study. Current Environmental Health Reports 10:1-11.
- Tejera, César Higgins , Erin Bakshis Ware, Lindsay Kobayashi, Mingzhou Fu, Margaret Takako Hicken, Zawistowski, Matthew, Mukherjee, Bhramar, Bakulski, Kelly M.. 2023. Decomposing interaction and mediating effects of race/ethnicity and circulating blood levels of cystatin C on cognitive status in the United States health and retirement study. Frontiers in Human Neuroscience 17
- Dominique L. Sylvers, Margaret Takako Hicken, Michael Esposito, Jennifer Manly, Suzanne Judd, Philippa J Clarke. 2022. Walkable Neighborhoods and Cognition: Implications for the Design of Health Promoting Communities. Journal of Aging and Health 34(6-8):893–904.
- Jang, Joy Bohyun, Margaret Hicken, Mullins, Megan, Esposito, Michael Hughes, Sol,Ketlyne, Manly, Jennifer J, Judd, Suzanne, Wadley, Virginia, Clarke,Philippa J. 2022. Racial segregation and cognitive function among older adults in the United States: Findings from the REasons for Geographic and Racial Differences in Stroke (REGARDS) study. The Journals of Gerontology: Series B 77(6):1132-1143.
- Ryan Gabriel, Private: Esposito, Michael Hughes, Geoff Ward, Hedwig Lee, Hicken, Margaret Takako, David Cunningham. 2021. White Health Benefits of Histories of Enslavement: The Case of Opioid Deaths. The ANNALS of the American Academy of Political and Social Science 694(1):142-156.
- Hicken, Margaret Takako, Lewis Miles, Haile,Solome, Private: Esposito, Michael Hughes. 2021. Linking History to Contemporary State-Sanctioned Slow Violence through Cultural and Structural Racism. The ANNALS of the American Academy of Political and Social Science 694(1):48-58.
- Gilbert C. Gee, Hicken, Margaret Takako. 2021. Structural Racism: The Rules and Relations of Inequity. Ethnicity & Disease (Suppl):293-300.
- Savannah Larimore, Mosi Ifatunji, Hedwig Lee, Rafferty, Jane, Private: Jackson, James Sidney, Hicken, Margaret Takako. 2021. Geographic Variation in Reproductive Health Among the Black Population in the US: An Analysis of Nativity, Region of Origin, and Division of Residence. Population Research and Policy Review 40(1):33-59.
- Saunders, Milda R., Ricardo, Ana C., Chen, Jinsong, Anderson, Amanda H., Cedillo-Couvert, Esteban A., Fischer, Michael J., Hernandez-Rivera, Jesus, Hicken, Margaret Takako, Hsu, Jesse Y., Zhang, Xiaoming, Hynes, Denise, Jaar, Bernard, Kusek, John W., Rao, Panduranga, Feldman, Harold I., Go, Alan S., Lash, James P.. 2020. Neighborhood socioeconomic status and risk of hospitalization in patients with chronic kidney disease: A chronic renal insufficiency cohort study. Medicine 99(28):e21028.
- Cathryn J. Lapedis, Laura H. Mariani, Jang, Bohyun, Jeffrey Hodgin, Hicken, Margaret Takako. 2020. Understanding the Link between Neighborhoods and Kidney Disease. Kidney360 1(8):845-854.